Effect of a Single Bout of Exercise on Autophagy Regulation in Skeletal Muscle of High-Fat High-Sucrose Diet-Fed Mice

초록 Autophagy maintains metabolic homeostasis of muscles, and its impairment may cause muscle dysfunction. Exercise can improve muscle dysfunction induced by long-term high-fat diet. This study aimed to explore the association of autophagy with impaired muscle dysfunction in obese conditions and investigate its relationship with exercise-induced muscle function improvement. 저자 장적적, 송욱, 이지현, 곽성은, 신형은 […]

Exercise, the Gut Microbiome, and Frailty

초록 The gut microbiome is deeply associated with both skeletal muscle and brain function. In particular, gut microbiome dysbiosis may accelerate age-related diseases by affecting these systems. Although there is increasing evidence of the correlations between the gut microbiome and skeletal muscle and brain, it remains unclear whether changes in the gut microbiome due to […]

Effects of Acute Aerobic Exercise on the Early Stage of Energy Metabolism Related Gene Expression in Mouse Gastrocnemius: Microarray Analysis

초록 The purpose of this study was to examine the infancy changes of metabolic gene expression level in mouse gastrocnemius muscle after after 1 hour acute treadmill exercise. METHODS C57BL/6 mouse were randomly divided into control (n=5) and 1 hour acute treadmill exercise intervention group (n=5). After the intervention, we extracted total mRNA from the […]

Potential role of exercise-induced glucose-6-phosphate isomerase in skeletal muscle function

초록  Recent studies have shown that glucose-6-phosphate isomerase (GPI)—which is a glycolysis interconversion enzyme—reduces oxidative stress. However, these studies are limited to tumors such as fibrosarcoma, and there are no studies that have examined the effects of exercise on GPI expression in mice skeletal muscle. Furthermore, GPI acts in an autocrine manner thorough its receptor, […]

Effect of Fingertip Temperature on Multi-finger Actions in Young Adults

초록 This study examined the effects of stimulating fingertip temperature on the patterns of force sharing and stability properties during multi-finger force production tasks. Method: 9 adult subjects (male: 3, female: 6, age:  26.11±4.01yrs26.11±4.01yrs , height:  169.22±5.97cm169.22±5.97cm , weight:  61.44±11.27kg61.44±11.27kg ) participated in this study. The experiment consisted of three blocks: 1) maximal voluntary contraction (MVC) task, 2) single-finger ramp task […]

프로축구선수의 평점과 경기력 평가 점수체계의 비교

초록 본 연구의 목적은 프로축구경기 종료 후 미디어 매체에서 발표하는 평점의 매체 간 특성을 탐색하고, 선행연구들에서 제시한 축구선수 경기력 평가 점수체계와 미디어 매체 평점 간의 관계를 확인하여 각 점수체계의 특성을 비교하는 것이다. 평점에 영향을 미치는 요인을 탐색하기 위해 중다회귀분석을 실시하여 매체 간 평점의 특성을 비교하였고, 미디어 매체의 평점과 선행연구들에서 제시한 축구선수 경기력 평가 점수체계와의 관계를 […]

10주 트레드밀 운동이 비만 쥐 혈관 내피세포의 오토파지 조절장애 개선에 미치는 효과

초록  Impaired autophagy, a conserved process for the cellular energy homeostasis by degrading damaged cytosolic constituents, is an important contributor to the pathogenesis of atherosclerosis. The purpose of this study was to determine whether regular aerobic exercise can improve obesity-induced dysregulation of autophagy in mice arterial endothelial cells.  저자 문효열, 김지석, 전태봉, 백경완, 유준일, 안상현 […]